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Prevalence of urinary incontinence and other pelvic floor disorders in women with myotonic dystrophy type 1

  • Isabelle Fisette-Paulhus
    Affiliations
    Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001, 12th Avenue Nord, Sherbrooke, Québec, Canada J1H 5N4
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  • Cynthia Gagnon
    Affiliations
    Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001, 12th Avenue Nord, Sherbrooke, Québec, Canada J1H 5N4

    Groupe de recherche interdisciplinaire sur les maladies neuromusculaires (GRIMN), Centre de recherche du CIUSSS du Saguenay–Lac-St-Jean – Hôpital de Jonquière, 2330, rue de l'Hôpital, Jonquière, Québec, Canada G7X 7X2
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  • Mélanie Morin
    Correspondence
    Corresponding author: Mélanie Morin, Full professor and researcher, School of Rehabilitation, Faculty of Medicine and Health Sciences, University of Sherbrooke, 3001, 12th Avenue Nord, Sherbrooke, Québec, Canada J1H 5N4. Tel.: 819-346-1110x13818.
    Affiliations
    Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001, 12th Avenue Nord, Sherbrooke, Québec, Canada J1H 5N4

    Groupe de recherche interdisciplinaire sur les maladies neuromusculaires (GRIMN), Centre de recherche du CIUSSS du Saguenay–Lac-St-Jean – Hôpital de Jonquière, 2330, rue de l'Hôpital, Jonquière, Québec, Canada G7X 7X2

    Research center of the Centre hospitalier universitaire de Sherbrooke, School of Rehabilitation, Faculty of Medicine, University of Sherbrooke, 3001, 12th Avenue Nord, Sherbrooke, Québec, Canada J1H 5N4
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Published:November 13, 2022DOI:https://doi.org/10.1016/j.nmd.2022.11.003

      HIGHLIGHTS

      • A variety of pelvic floor disorders can be present in women with DM1.
      • Urinary incontinence (60.0%) is prevalent among women with DM1.
      • Anal incontinence (56.3%), mainly flatal incontinence, is also frequent in women with DM1.
      • The phenotype is associated with prevalence of anal incontinence and abdominal pain and urinary incontinence severity.
      • Colorectal-anal symptoms had a high impact on participation and emotional domains.

      ABSTRACT

      Myotonic dystrophy type 1 (DM1) is a neuromuscular disease that can affect the pelvic floor muscles but few studies have investigated pelvic floor disorders, including urinary incontinence. The main purpose of this study was to document the prevalence, characteristics, and impacts of urinary incontinence and other pelvic floor disorders in women with DM1. Associations between pelvic floor disorders and phenotypes, considering age and parity, were explored. Eighty adult women aged 47,1±13,7 years old participated in a cross-sectional study using validated questionnaires, including the International Consultation Incontinence Questionnaire – Urinary Incontinence short form (ICIQ-UI-SF)), the Pelvic Floor Disorder Inventory (PFDI), and the Pelvic Floor Impact Questionnaire short form (PFIQ-SF). The mean score for the ICIQ-UI-SF was 4.3. The mean scores for the subscales of the PFDI were 36.8 for the urinary distress inventory, 74.1 for the colorectal-anal distress inventory, and 43.8 for the pelvic organ prolapse distress inventory. A total of 60% of women reported urinary incontinence and 56.3% anal incontinence. Pelvic prolapse symptoms (>1 symptom) were reported by 25% of women. Findings reveal high prevalence and significant related impacts of these disorders. This provides evidence regarding the importance of screening for these disorders in a clinical setting and the need to explore treatment approaches.

      Keywords

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