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246th ENMC International Workshop: Protein aggregate myopathies 24–26 May 2019, Hoofddorp, The Netherlands

Published:November 13, 2020DOI:https://doi.org/10.1016/j.nmd.2020.11.003
      Twenty participants including one patient representative from European countries, USA, Australia and Japan attended the 246th ENMC-sponsored workshop, the sixth one focusing on protein aggregate myopathies (PAM) [
      • Goebel H.H.
      • Fardeau M.
      Desmin in myology. 24th European neuromuscular center (ENMC)-sponsored international workshop, 5-7 November 1993, Naarden, The Netherlands.
      ,
      • Goebel H.H.
      • Fardeau M.
      Familial desmin-related myopathies and cardiomyopathies - from myopathology to molecular and clinical genetics. 36th European neuromuscular centre (ENMC)-sponsored International Workshop, 20-22 October 1995, Naarden, The Netherlands.
      ,
      • Goebel H.H.
      • Fardeau M.
      Desmin - protein surplus myopathies, 96th European neuromuscular centre (ENMC)-sponsored international workshop, September 14-16, 2001, Naarden, The Netherlands.
      ,
      • Goebel H.H.
      • Fardeau M.
      121st ENMC international workshop on desmin and protein aggegate myopathies. 7-9 November 2003, Naarden, The Netherlands.
      ,
      • Goebel H.H.
      • Fardeau M.
      • Olivé M.
      • Schröder R.
      156th ENMC international workshop: desmin and protein aggregate myopathies, 9-11 November 2007, Naarden, The Netherlands.
      ]. Since the last ENMC Workshop on PAM in November 2007, a multitude of novel insights into clinical aspects, genetic bases and molecular pathogenesis of these diseases have been gained. The attending experts discussed recent discoveries of new disease entities, the morphological spectrum of protein aggregation and new pathophysiological and pharmacological treatment aspects derived from animal and cell models.
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