Neuromuscular Disorders
Volume 20, Issue 3 , Pages 155-161 , March 2010

The Children’s Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP INTEND): Test development and reliability

  • A.M. Glanzman

      Affiliations

    • Department of Physical Therapy, Children’s Hospital of Philadelphia, 3405 Civic Center Blvd., Philadelphia, PA 19104, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 610 892 7768; fax: +1 215590 9162.
    • ,
  • E. Mazzone

      Affiliations

    • Department of Paediatric Neurology, Catholic University, Rome, Italy
    • ,
  • M. Main

      Affiliations

    • Dubowitz Neuromuscular Centre, Great Ormond Street Children’s Hospital, London, UK
    • ,
  • M. Pelliccioni

      Affiliations

    • Department of Paediatric Neurology, Catholic University, Rome, Italy
    • ,
  • J. Wood

      Affiliations

    • Primary Children’s Medical Center, Salt Lake City, UT, USA
    • ,
  • K.J. Swoboda

      Affiliations

    • Departments of Neurology and Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA
    • ,
  • C. Scott

      Affiliations

    • CBS Squared Inc., Fort Washington, PA, USA
    • ,
  • M. Pane

      Affiliations

    • Department of Paediatric Neurology, Catholic University, Rome, Italy
    • ,
  • S. Messina

      Affiliations

    • Department of Paediatric Neurology, Catholic University, Rome, Italy
    • Department of Neuroscience, Psychiatry and Anaesthesiology, University of Messina, Messina, Italy
    • ,
  • E. Bertini

      Affiliations

    • Department of Laboratory Medicine, Unit of Molecular Medicine, Bambino Gesù Hospital, Rome, Italy
    • ,
  • E. Mercuri

      Affiliations

    • Department of Paediatric Neurology, Catholic University, Rome, Italy
    • Dubowitz Neuromuscular Centre, University College London, UK
    • ,
  • R.S. Finkel

      Affiliations

    • Departments of Neurology and Pediatrics, Children’s Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, PA, USA

Received 21 July 2009 ,Revised 16 November 2009 ,Accepted 27 November 2009.

References 

  1. Ludvigsson P, Olafsson E, Hauser WA. Spinal muscular atrophy. Incidence in Iceland. Neuroepidemiology. 1999;18:265–269
  2. Lefebvre S, Burglen L, Reboullet S, et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell. 1995;80:155–165
  3. Monani UR, Lorson CL, Parsons DW, et al. A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2. Hum Mol Genet. 1999;8:1177–1183
  4. Feldkotter M, Schwarzer V, Wirth R, Wienker TF, Wirth B. Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy. Am J Hum Genet. 2002;70:358–368
  5. Sumner CJ. Therapeutics development for spinal muscular atrophy. NeuroRx. 2006;3:235–245
  6. Russman BS. Spinal muscular atrophy: clinical classification and disease heterogeneity. J Child Neurol. 2007;22:946–951
  7. Zerres K, Rudnik-Schoneborn S. Natural history in proximal spinal muscular atrophy. Clinical analysis of 445 patients and suggestions for a modification of existing classifications. Arch Neurol. 1995;52:518–523
  8. Iannaccone ST. Modern management of spinal muscular atrophy. J Child Neurol. 2007;22:974–978
  9. Zerres K, Rudnik-Schoneborn S, Forrest E, Lusakowska A, Borkowska J, Hausmanowa-Petrusewicz I. A collaborative study on the natural history of childhood and juvenile onset proximal spinal muscular atrophy (type II and III SMA): 569 patients. J Neurol Sci. 1997;146:67–72
  10. Finkel RS, Hynan LS, Glanzman AM, et al. The test of infant motor performance: reliability in spinal muscular atrophy type I. Pediatr Phys Ther. 2008;20:242–246
  11. Dubowitz LMS, Dubowitz V, Mercuri E. The neurological assessment of the preterm and full-term newborn infant. 2nd ed. Mac Keith Press; 1999.
  12. Piper MC, Darrah J. Motor assessment of the developing infant. Philadelphia: WB Saunders Co; 1994;
  13. Folio MR, Fewell RR. Peabody developmental motor scales. 2nd ed.. Austin: PRO-ED; 2000;
  14. Bayley N. Manual for the bayley scales of infant development. 2nd ed.. San Antonio: Psychological Corp; 1993;
  15. Campbell SK. The test of infant motor performance: test user’s manual, version 2.0: a training manual. Chicago: Infant Motor Performance Scales; 2005;
  16. Bosboom WM, Vrancken AF, van den Berg LH, Wokke JH, Iannaccone ST. Drug treatment for spinal muscular atrophy type I. Cochrane Database Syst Rev 2009; CD006281.
  17. Brazelton TB, Nugent JK. The neonatal behavioral assessment scale. Cambridge: Mac Keith Press; 1995;
  18. O’Hagen J. An expanded version of the Hammersmith functional motor scale for SMA II and III patients. Neuromuscul Disord. 2007;17:693–697
  19. Cronbach L. Coefficient alpha and the internal structure of tests. Psychometrika. 1951;16:297–334

PII: S0960-8966(09)00698-1

doi: 10.1016/j.nmd.2009.11.014

Neuromuscular Disorders
Volume 20, Issue 3 , Pages 155-161 , March 2010

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