Neuromuscular Disorders
Volume 20, Issue 2 , Pages 102-110, February 2010

Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials

  • Linda J. Popplewell

      Affiliations

    • School of Biological Sciences, Royal Holloway – University of London, Egham, Surrey TW20 0EX, United Kingdom
    • These authors contributed equally to this paper.
  • ,
  • Carl Adkin

      Affiliations

    • Dubowitz Neuromuscular Centre, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
    • These authors contributed equally to this paper.
  • ,
  • Virginia Arechavala-Gomeza

      Affiliations

    • Dubowitz Neuromuscular Centre, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
  • ,
  • Annemieke Aartsma-Rus

      Affiliations

    • Center for Human and Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands
  • ,
  • Christa L. de Winter

      Affiliations

    • Center for Human and Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands
  • ,
  • Steve D. Wilton

      Affiliations

    • Centre for Neurological and Neuromuscular Disorders, Australian Neuromuscular Research Institute, University of Western Australia, Perth, WA 6009, Australia
  • ,
  • Jennifer E. Morgan

      Affiliations

    • Dubowitz Neuromuscular Centre, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
  • ,
  • Francesco Muntoni

      Affiliations

    • Dubowitz Neuromuscular Centre, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
  • ,
  • Ian R. Graham

      Affiliations

    • School of Biological Sciences, Royal Holloway – University of London, Egham, Surrey TW20 0EX, United Kingdom
  • ,
  • George Dickson

      Affiliations

    • School of Biological Sciences, Royal Holloway – University of London, Egham, Surrey TW20 0EX, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 (0)1784 443870; fax: +44 (0)1784 414224.

Received 13 July 2009; received in revised form 20 October 2009; accepted 27 October 2009.

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PII: S0960-8966(09)00666-X

doi:10.1016/j.nmd.2009.10.013

Neuromuscular Disorders
Volume 20, Issue 2 , Pages 102-110, February 2010