Neuromuscular Disorders
Volume 19, Issue 12 , Pages 822-824 , December 2009

Oestrogen receptor alpha gene intronic polymorphisms and autoimmune myasthenia gravis in Caucasian women

  • Zsuzsanna Pal

      Affiliations

    • Center for Molecular Neurology, Department of Neurology, Semmelweis University, Budapest, Hungary
    • Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary
    • ,
  • Anikó Gal

      Affiliations

    • Center for Molecular Neurology, Department of Neurology, Semmelweis University, Budapest, Hungary
    • ,
  • Viktória Remenyi

      Affiliations

    • Center for Molecular Neurology, Department of Neurology, Semmelweis University, Budapest, Hungary
    • ,
  • Attila Tordai

      Affiliations

    • Molecular Diagnostics Laboratory, National Institute of Blood Transfusion, Budapest, Hungary
    • ,
  • Maria Judit Molnar

      Affiliations

    • Center for Molecular Neurology, Department of Neurology, Semmelweis University, Budapest, Hungary
    • Corresponding Author InformationCorresponding author. Address: Center for Molecular Neurology, Department of Neurology, Semmelweis University, Tömő u. 25-29, 1083 Budapest, Hungary. Tel./fax: +36 14591492.

Received 14 July 2009 ,Revised 1 September 2009 ,Accepted 7 September 2009.

References 

  1. Delpy L, Douin-Echinard V, Garidou L, Bruand C, Saoudi A, Guéry J-C. Estrogen enhances susceptibility to experimental autoimmune myasthenia gravis by promoting type 1-polarized immune responses. J Immunol. 2005;175:5050–5057
  2. Nancy P, Berrih-Aknin S. Differential oestrogen receptor expression in autoimmune myasthenia gravis. Endocrinology. 2005;5:2345–2353
  3. Ushiyama T, Mori K, Inoue K, Huang J, Nishioka J, Hukuda S. Association of oestrogen receptor gene polymorphisms with age at onset of rheumatoid arthritis. Ann Rheum Dis. 1999;58:7–10
  4. Lee YJ, Shin KS, Kang SW, et al. Association of the oestrogen receptor a gene polymorphisms with disease onset in systemic lupus erythematosus. Ann Rheum Dis. 2004;63:1244–1249
  5. Niino M, Kikuchi S, Fukazawa T, Yabe I, Tashiro K. Estrogen receptor gene polymorphism in Japanese patients with multiple sclerosis. J Neurol Sci. 2000;179:70–75
  6. Jakimiuk A, Nowicka M, Bogusiewicz M, et al. Prevalence of estrogen receptor PvuII and XbaI polymorphism in population of Polish postmenopausal women. Folia Histochem Cytobiol. 2007;45:331–338
  7. Savettieri G, Cittadella R, Valentino P, et al. Lack of association between estrogen receptor 1 gene polymorphisms and multiple sclerosis in southern Italy in humans. Neurosci Lett. 2002;327:115–118

PII: S0960-8966(09)00596-3

doi: 10.1016/j.nmd.2009.09.002

Neuromuscular Disorders
Volume 19, Issue 12 , Pages 822-824 , December 2009

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