Neuromuscular Disorders
Volume 19, Issue 7 , Pages 502-506 , July 2009

Developing standard procedures for murine and canine efficacy studies of DMD therapeutics: report of two expert workshops on “Pre-clinical testing for Duchenne dystrophy”: Washington DC, October 27th–28th 2007 and Zürich, June 30th-July 1st 2008

  • Kanneboyina Nagaraju

      Affiliations

    • Research Center for Genetic Medicine, Children’s National Medical Center, Washington DC, USA
  • ,
  • Raffaella Willmann

      Affiliations

    • Biozentrum, University of Basel, Basel, Switzerland
    • Corresponding Author InformationCorresponding author.
  • ,
  • on Behalf of the TREAT-NMD Network and the Wellstone Muscular Dystrophy Cooperative Research Network

Received 6 April 2009 ,Revised 6 May 2009 ,Accepted 13 May 2009.

References 

  1. Willmann R, Possekel S, Dubach-Powell J, Meier T, Ruegg MA. Mammalian animal models for Duchenne muscular dystrophy. Neuromuscul Disord. 2009;19(4):241–249
  2. Grounds MD, Radley HG, Lynch GS, Nagaraju K, De Luca A. Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy. Neurobiol Dis. 2008;31(1):1–19
  3. Spurney CF, Gordish-Dressman H, Guerron AD, et al. Pre-clinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measures. Muscle Nerve. 2009;39(5):591–602

PII: S0960-8966(09)00123-0

doi: 10.1016/j.nmd.2009.05.003

Neuromuscular Disorders
Volume 19, Issue 7 , Pages 502-506 , July 2009