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Neuromuscular Disorders
Volume 17, Issue 8
, Pages 655-660
, August 2007
141st ENMC International Workshop Inaugural Meeting of the EURO-Laminopathies Project Nuclear Envelope-linked Rare Human Diseases: From Molecular Pathophysiology towards Clinical Applications 10–12 March 2006, Naarden, The Netherlands
References
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- . Human laminopathies: nuclei gone genetically awry. Nat Rev Genet. 2006;7:940–952
- . A-type lamin complexes and regenerative potential: a step towards understanding laminopathic diseases?. Histochem Cell Biol. 2006;125:33–41
- . A-type lamins: guardians of the soma?. Nat Cell Biol. 2004;6:1062–1067
- Vlcek S, Foisner R. A-type lamin networks in light of laminopathic diseases. Biochim Biophys Acta 2006, published online.
- . Lamina-associated polypeptide 2{alpha} regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway. J Cell Biol. 2006;173:83–93
- . Nucleoplasmic LAP2{alpha}-lamin A complexes are required to maintain a proliferative state in human fibroblasts. J Cell Biol. 2007;176:163–172
- . Intermediate filaments: molecular structure, assembly mechanism, and integration into functionally distinct intracellular Scaffolds. Annu Rev Biochem. 2004;73:749–789
- . Solubility properties and specific assembly pathways of the B-type lamin from Caenorhabditis elegans. J Struct Biol. 2006;155:340–350
- . Intermediate filament assembly: fibrillogenesis is driven by decisive dimer–dimer interactions. Curr Opin Struct Biol. 1998;8:177–185
- . Nuclear lamins: their structure, assembly, and interactions. J Struct Biol. 1998;122:42–66
- . Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly. Embo J. 2002;21:1255–1266
- . Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins. J Mol Biol. 2004;343:1067–1080
- . Lamins: building blocks or regulators of gene expression?. Nat Rev Mol Cell Biol. 2002;3:848–858
- . Flow-induced hardening of endothelial nucleus as an intracellular stress-bearing organelle. J Biomech. 2005;38:1751–1759
- . Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells. J Cell Biol. 2005;170:781–791
- . The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy. Structure. 2002;10:811–823
- . Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat Rev Genet. 2001;2:292–301
- . Beyond the sequence: cellular organization of genome function. Cell. 2007;128:787–800
- . The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. Hum Mol Genet. 2001;10:211–219
- . Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci USA. 2006;103:8703–8708
- . Reversal of the cellular phenotype in the premature aging disease Hutchinson–Gilford progeria syndrome. Nat Med. 2005;11:440–445
- . Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson–Gilford progeria syndrome. Proc Natl Acad Sci USA. 2004;101:8963–8968
- . Altered prelamin A processing is a common mechanism leading to lipodystrophy. Hum Mol Genet. 2005;14:1489–1502
- . Nuclear lamins, diseases and aging. Curr Opin Cell Biol. 2006;18:335–341
- . Rescue of heterochromatin organization in Hutchinson–Gilford progeria by drug treatment. Cell Mol Life Sci. 2005;62:2669–2678
- . Age-related changes of nuclear architecture in Caenorhabditis elegans. Proc Natl Acad Sci USA. 2005;102:16690–16695
- . Lamin A-dependent nuclear defects in human aging. Science. 2006;312:1059–1063
- . Stabilization of the retinoblastoma protein by A-type nuclear lamins is required for INK4A-mediated cell cycle arrest. Mol Cell Biol. 2006;26:5360–5372
- . A-type lamins are essential for TGF-beta1 induced PP2A to dephosphorylate transcription factors. Hum Mol Genet. 2005;14:2839–2849
- . Expression of a mutant lamin A that causes Emery-Dreifuss muscular dystrophy inhibits in vitro differentiation of C2C12 myoblasts. Mol Cell Biol. 2004;24:1481–1492
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PII: S0960-8966(07)00138-1
doi: 10.1016/j.nmd.2007.04.003
© 2007 Elsevier B.V. All rights reserved.
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Neuromuscular Disorders
Volume 17, Issue 8
, Pages 655-660
, August 2007
